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An atlas of genetic correlations across human diseases and traits. Introduction Characterizing the effects of saturated fat intake on obesity and metabolic health continues to be a major challenge. These differences are linked to sex hormones, as estradiol enhances taste cell responsiveness to fatty acids during periods of low circulating estrogen following ovariectomy and in males. We compared the direction of the effects for overlapping GWAS results by estimating the effects of lead body fat ratio-associated SNPs on the respective overlapping anthropometric traits. Clegg, D. Fig 5. Factors affecting intestinal absorption of highly lipophilic food microconstituents fat-soluble vitamins, carotenoids and phytosterols. For instance, inflammation is part of the normal immune response, and fat tissue produces some molecules that increase inflammation and others that suppress it. Interactions of IGF-1 with the blood-brain barrier in vivo and in situ. Kathiresan, S. Cross-sex hormone therapy affects body fat distribution in transgender persons Authors. Fertility and Sterility, 94 3 ,
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